Browsing by Author "Koyutürk, Meral"
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Effect of glurenorm on immunohistochemical changes in pancreatic ? cells of rats in experimental diabetes
Immunohistochemical localization of islets of Langerhans of streptozotocin (65 mg/kg ip) induced diabetic + glurenorm (10 mg/kg po) treated female albino rats revealed increase in number of ? cells and insulin immunoreactivity ... -
Effects of leucocytospermia on semen parameters and outcomes of intracytoplasmic sperm injection
Yılmaz, Seda; Koyutürk, Meral; Kılıç, Gülleyla; Alpak, Olcay; Aytoz, Ayşe (Wiley, 2005)Leucocytes are present throughout the male reproductive tract but the clinical significance of leucocytic infiltration in the human ejaculate is controversial. The World Health Organization (WHO) defines leucocytospermia ... -
Effects of vanadyl sulfate on liver of streptozotocin-induced diabetic rats
Koyutürk, Meral; Tunali, Sevim; Bolkent, Şehnaz; Yanardağ, Refiye (Humana Press Inc., 2005)The aim of this study was to investigate the microscopic and biochemical effects of vanadyl sulfate on liver tissue of normal and streptozotocin (65 mg/kg) diabetic rats. Vanadyl sulfate was administered by gavage at a ... -
The effects of vitamin C vitamin E and selenium against cadmium toxicity on liver of rats
Yanardağ, Refiye; Koyutürk, Meral; Bolkent, Şehnaz; Tunalı, Sevim (Histochemical Soc Inc, 2004)[Abstract Not Available] -
Evaluation of the proliferating activities of normal and carcinomatous prostatic tissues with Ki-67
Koyutürk, Meral; Kılıçarslan, Işın; Aytekin, Yener (Haliç Üniv. Fen Edebiyat Fak., 2005)In this study proliferation activities of normal prostate tissue, benign prostate hyperplasia (BPH), prostatic intraepithelial neoplasia (PIN) and prostate cancer samples were evaluated immunohistochemically by using ... -
Ginkgo biloba extract regulates differentially the cell death induced by hydrogen peroxide and simvastatin
Altıok, Nedret; Ersöz, Melike; Karpuz, Vildan; Koyutürk, Meral (Elsevier Science Bv, 2006)Several human diseases have been associated with the overproduction of reactive oxygen species (ROS) and subsequently various antioxidants emerged as potential therapeutic agents that scavenge ROS. As an oxidative stress ... -
Hydrogen peroxide induces apoptosis of glioma cells via JNK activation
Koyutürk, Meral; Altıok, Nedret (Histochemical Soc Inc, 2004)[Abstract Not Available] -
Influence of combined antioxidants against cadmium induced testicular damage
Koyutürk, Meral; Yanardağ, Refiye; Bolkent, Şehnaz; Tunalı, Sevim (Elsevier Science Bv, 2006)Acute effects ofcadmium (Cd) and combined antioxidants were evaluated in Sprague-Dawley rat testes. The rats were subdivided into four groups. Cadmium chloride (2 mg/kg day) injected intraperitoneally during 8 days. Vitamin ... -
Lökositosperminin semen ve intrasitoplazmik sperm enjesksiyonu parametreleri üzerine etkileri
Macit, Seda (Kadir Has Üniversitesi, 2004)İnfertilite, korunmasız olarak cinsel ilişkiye girilmesine rağmen, bir yılı aşan süreyle çiftlerin çocuk sahibi olamamasıdır. İnfertilite nedeniyle başvuran çiftlere yapılan araştırmalar sonunda, gerekirse yardımla üreme ... -
Preeklamptik ve normal plasentada endotelyal nitrik oksit sentetaz immünreaktivitesinin incelenmesi
Mutlu, Canan; Koyutürk, Meral; Karpuz, Vildan (2005)Bu çalışmada amaç, uteroplasental değişikliklerle ilişkili olduğu düşünülen endotelyal nitrik oksit sentetaz düzeylerinin (eNOS) preeklamptik ve kontrol gebelere ait fetal ve maternal yüz plasentalarında immünohistokimyasal ... -
Preeklamptik ve normal plasentada endotelyal nitrik oksit sentetaz immunreaktivitesinin incelenmesi
Mutlu, Canan (Kadir Has Üniversitesi, 2004)Çalışmada, 10 preeklamptik ve 5 normal kontrol grubu gebeye ait plasenta örnekleri ve kan değerleri incelendi. Son trimestir vakalarından proteinüri ve yüksek kan basıncı (> 140/90 mm/Hg) değerlerine göre preeklampsi ve ... -
The protective effect of vitamin C vitamin E and selenium combination therapy on ethanol-induced duodenal mucosal injury
Koyutürk, Meral; Bolkent, Şehnaz; Özdil, S; Arbak, Serap; Yanardağ, Refiye (Arnold Hodder Headline Plc., 2004)In this study the effect of a combination of vitamin C vitamin E and selenium on ethanol-induced duodenal mucosal damage in rats was investigated morphologically and biochemically. The duodenal mucosal injury was produced ... -
Protective effects of ascorbic acid DL-alpha-tocopherol acetate and sodium selenate on ethanol-induced gastric mucosal injury of rats
Özdil, Sadakat; Refiye, Yanardağ; Koyutürk, Meral; Bolkent, Şehnaz; Arbak, Serap (Humana Press Inc., 2004)In this study the effect of ascorbic acid (vitamin C) DL-alpha-tocopherol acetate (vitamin E) and sodium selenate (selenium) on ethanol-induced gastric mucosal injury in rats was investigated morphologically and biochemically. ... -
Simvastatin induces proliferation inhibition and apoptosis in C6 glioma cells via c-jun N-terminal kinase
Koyutürk, Meral; Ersöz, Melike; Altıok, Nedret (Elsevier Ireland Ltd., 2004)The lipid-lowering drugs statins induce apoptosis in a variety of tumor cells. Here we investigated the apoptotic effect of the lipophilic statin simvastatin in C6 glioma cells and the underlying effects on intracellular ... -
Spermatozoon ve reaktif oksijen türevleri
Yılmaz, Seda; Alpak, Olcay; Koyutürk, Meral (2005)Reaktif oksijen türevleri (ROT), biyokimyasal olaylar zincirinde oksijenin organik maddelerle etkileşimi sonucu ortaya çıkan reaktif ara ürünlerdir. ROT’nin fizyolojik mekanizmalar›n düzenlenmesinde rol aldıkları ... -
Sıçan tiroid bezinde kadmiyum hasarına karşı C vitamini, E vitamini ve selenyumun kombine kullanımının etkileri
Bulan, Karabulut Ömür; Koyutürk, Meral; Bolkent, Şehnaz; Yanardağ, Refiye; Oğuz, Tabakoğlu Ayşe (2004)Çalışmanın amacı sıçan tiroid bezinde kadmiyumun sebep olduğu hasara karşı C vitamini, E vitamini ve selenyumun koruyucu bir etkisinin olup olmadığını incelemek ve metallotionein ekspresyonunu tespit etmekti. Grup I: ... -
Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis
Koyutürk, Meral (2005)Purpose: Ion channel activity is involved in several basic cellular behaviors that are integral to metastasis (e.g., proliferation, motility, secretion, and invasion), although their contribution to cancer progression has ...